Home > Category > Signaling Pathways > Neuronal Signaling > mGluR > LY341495 (Synonyms:(2S)-2-Amino-2-[(1S,2S)-2-carboxycycloprop-1-yl]-3-(xanth-9-yl) propanoic acid)

LY341495 (Synonyms:(2S)-2-Amino-2-[(1S,2S)-2-carboxycycloprop-1-yl]-3-(xanth-9-yl) propanoic acid)

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Catalog No:CL2512 CAS No.:201943-63-7 MDLNo: Formula:C20H19NO5 MW:353.37
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2 mg 3-5days $163.00 Visible after login
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5 mg 3-5days $275.00 Visible after login
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10 mg 3-5days $420.00 Visible after login
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Product Overview
Product Name LY341495 (Synonyms:(2S)-2-Amino-2-[(1S,2S)-2-carboxycycloprop-1-yl]-3-(xanth-9-yl) propanoic acid)
CAS201943-63-7
FormulaC20H19NO5
MW353.37
Appearance White to off-white powder
Storage condition Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Product details

LY 341495 is a potent and selective orthosteric antagonist for the group II metabotropic glutamate receptors (mGluR2/3). Ki/IC50 values of LY-341495 are 2.3, 1.3, 173, 990, 6800, 8200 and 22000 nM for human mGlu2, mGlu3, mGlu8 , mGlu7a, mGlu1a, mGlu5a and mGlu4a receptors respectively. It is used in scientific research in several different areas, showing antidepressant effects in animal models, increasing the behavioural effects of hallucinogenic drugs in animal tests, and increasing the analgesic effects of μ-opioid agonists, as well as modulating dopamine receptor function.
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