D-erythro-Sphingosine | (2S,3R,4E)-2-Amino-4-Octadecene-1,3-Diol

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
5 mg	3-5days	$56.00	Visible after login	- +
10 mg	3-5days	$88.00	Visible after login	- +
25 mg	3-5days	$146.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

5 mg

3-5days

$56.00

Visible after login

- +

10 mg

3-5days

$88.00

Visible after login

- +

25 mg

3-5days

$146.00

Visible after login

- +

Product Overview

Product Name	D-erythro-Sphingosine \| (2S,3R,4E)-2-Amino-4-Octadecene-1,3-Diol \| (E,2S,3R)-2-Aminooctadec-4-Ene-1,3-Diol \| D-erythro-Sphingosine(DES)
CAS	123-78-4
Formula	C18H37NO2
MW	299.49
MDL	MFCD00036751
Appearance	White crystalline powder
Storage condition	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year

Product details

D-erythro-Sphingosine (Erythrosphingosine) is a very potent activator of p32-kinase with an EC₅₀ of 8 μM, and inhibits protein kinase C (PKC). D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator.

Related literature

Regulation of sphingosine-activated protein kinases: selectivity of activation by sphingoid basesand inhibition by non-esterified fatty acids.

PMID: 8379926 PMCID: PMC1134519 DOI: 10.1042/bj2940699

A concise synthesis of a promising protein kinase C inhibitor: D-erythro-Sphingosine.

PMID: 17328238 DOI: 10.1007/BF02977774

Protein phosphatase 2A (PP2A) activation promotes axonal growth and recovery in the CNS.

PMID: 26671085 DOI: 10.1016/j.jns.2015.10.025