Exatecan Mesylate (DX8951f) supplier | purchase Exatecan Mesylate (DX8951f) | Exatecan Mesylate (DX8951f) manufacturer | Exatecan Mesylate distributor|CAS 169869-90-3

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
25 mg	3-5 days	$68.00	Visible after login	- +
50 mg	3-5 days	$108.00	Visible after login	- +
100 mg	3-5 days	$182.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

25 mg

3-5 days

$68.00

Visible after login

- +

50 mg

3-5 days

$108.00

Visible after login

- +

100 mg

3-5 days

$182.00

Visible after login

- +

Product Overview

Product Name	Exatecan Mesylate (Synonyms: DX8951f)
CAS	169869-90-3
Formula	C25H26FN3O7S
MW	531.55
MDL	MFCD04113012
Appearance	Light yellow to green yellow powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Exatecan, also known as DX 8951, is semisynthetic, water-soluble camptothecin derivative with antineoplastic activity. Exatecan mesylate inhibits topoisomerase I activity by stabilizing the cleavable complex between topoisomerase I and DNA and inhibiting religation of DNA breaks, thereby inhibiting DNA replication and triggering apoptotic cell death. This agent does not require enzymatic activation and exhibits greater potency than camptothecin and other camptothecin analogues.

Exatecan Mesylate (DX8951f) supplier | purchase Exatecan Mesylate (DX8951f) | Exatecan Mesylate (DX8951f) manufacturer | Exatecan Mesylate distributor |CAS 169869-90-3

Related literature

Efficacy of camptothecin analog DX-8951f (Exatecan Mesylate) on human pancreatic cancer in an orthotopic metastatic model.

PMID: 12517781

A new water-soluble camptothecin derivative, DX-8951f, exhibits potent antitumor activity against human tumors in vitro and in vivo.

PMID: 7559102 PMCID: PMC5920901 DOI: 10.1111/j.1349-7006.1995.tb02468.x

DX-8951f, a water-soluble camptothecin analog, exhibits potent antitumor activity against a human lung cancer cell line and its SN-38-resistant variant.

PMID: 9259410 DOI: 10.1002/(sici)1097-0215(19970807)72:4<680::aid-ijc21>3.0.co;2-e

Sorry, no related items

History

CL2725A

Exatecan Mesylate (Synonyms: DX8951f)

169869-90-3 99+%

Exatecan Mesylate (Synonyms: DX8951f)

Chemical safety data sheet(MSDS)