PD 169316

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
5 mg	3-5days	$108.00	Visible after login	- +
10 mg	3-5days	$168.00	Visible after login	- +
25 mg	3-5days	$266.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

5 mg

3-5days

$108.00

Visible after login

- +

10 mg

3-5days

$168.00

Visible after login

- +

25 mg

3-5days

$266.00

Visible after login

- +

Product Overview

Product Name	PD 169316
CAS	152121-53-4
Formula	C20H13FN4O2
MW	360.34
Appearance	Light yellow to yellow powder
Storage condition	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

Product details

PD 169316 is a potent, selective and cell-permeable p38 MAP kinase inhibitor with IC50 of 89 nM. PD169316 abrogates signaling initiated by both TGFbeta and Activin A. PD169316 shows antiviral activity against Enterovirus71.

Related literature

PD169316, a specific p38 inhibitor, shows antiviral activity against Enterovirus71

PMID: 28545002 DOI: 10.1016/j.virol.2017.05.012

Suppression of Nestin reveals a critical role for p38-EGFR pathway in neural progenitor cell proliferation.

PMID: 27894083 PMCID: PMC5349970 DOI: 10.18632/oncotarget.13498

p38 and p42/44 MAPKs differentially regulate progesterone receptor A and B isoform stabilization.

PMID: 21816898 PMCID: PMC3551571 DOI: 10.1210/me.2011-1042

The p38 MAPK inhibitor, PD169316, inhibits transforming growth factor beta-induced Smad signaling in human ovarian cancer cells.

PMID: 14521923 DOI: 10.1016/j.bbrc.2003.09.021

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History

CL2908