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SL 327

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Catalog No:CL2945 CAS No.:305350-87-2 MDLNo:MFCD06411432 Formula:C16H12F3N3S MW:335.35
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Product Overview
Product Name SL 327
CAS305350-87-2
FormulaC16H12F3N3S
MW335.35
MDLMFCD06411432
AppearanceWhite to off-white powder
Storage conditionStore in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.
Product details

SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/ 0.22 μM, no activity towards Erk1, MKK3, MKK4, c-JUN, PKC, PKA, or CamKII; capable of transport through the blood-brain barrier.


Related literature

Current Development Status of MEK Inhibitors.

PMID: 28954413 PMCID: PMC6151813 DOI: 10.3390/molecules22101551

A necessity for MAP kinase activation in mammalian spatial learning

PMID: 10541468 PMCID: PMC311312 DOI: 10.1101/lm.6.5.478

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