Deucravacitinib | BMS-986165 | CAS 1609392-27-9 | JAK inhibitor

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
1 mg	In-stock	$78.00	Visible after login	- +
5 mg	In-stock	$188.00	Visible after login	- +
10 mg	In-stock	$348.00	Visible after login	- +
25 mg	In-stock	$618.00	Visible after login	- +
50 mg	In-stock	$906.00	Visible after login	- +
100 mg	In-stock	$1276.00	Visible after login	- +
250 mg	In-stock	$1638.00	Visible after login	- +
500 mg	In-stock	$2256.00	Visible after login	- +
1 g	In-stock	$3656.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

1 mg

In-stock

$78.00

Visible after login

- +

5 mg

In-stock

$188.00

Visible after login

- +

10 mg

In-stock

$348.00

Visible after login

- +

25 mg

In-stock

$618.00

Visible after login

- +

50 mg

In-stock

$906.00

Visible after login

- +

100 mg

In-stock

$1276.00

Visible after login

- +

250 mg

In-stock

$1638.00

Visible after login

- +

500 mg

In-stock

$2256.00

Visible after login

- +

1 g

In-stock

$3656.00

Visible after login

- +

Product Overview

Product Name	Deucravacitinib (Synonyms: BMS-986165)
CAS	1609392-27-9
Formula	C20H19D3N8O3
MW	425.46
MDL	MFCD31715455
Appearance	Off-white to light yellow powder
Storage condition	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

Product details

Deucravacitinib (BMS-986165) inhibits IL-12/23 and type I IFN pathways. BMS-986165 is a highly selective, orally bioavailable allosteric TYK2 inhibitor for the treatment of autoimmune diseases. Which selectively binds to TYK2 pseudokinase (JH2) domain (IC50=1.0 nM) and blocks receptor-mediated Tyk2 activation by stabilizing the regulatory JH2 domain.

Related literature

Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for the Treatment of Autoimmune Diseases: Discovery of the Allosteric Inhibitor BMS-986165.

PMID: 31318208 DOI: 10.1021/acs.jmedchem.9b00444

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History

CL2962

Deucravacitinib (Synonyms: BMS-986165)

1609392-27-9 Purity: 99.73%

Deucravacitinib (Synonyms: BMS-986165)

Chemical safety data sheet(MSDS)

Certificate Of Authenticity(CPA)