Brigimadlin (BI 907828) supplier | Brigimadlin (BI 907828) manufacturer | Brigimadlin (BI 907828) distributor

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
1 mg	3-5 days	$268.00	Visible after login	- +
5 mg	3-5 days	$588.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

1 mg

3-5 days

$268.00

Visible after login

- +

5 mg

3-5 days

$588.00

Visible after login

- +

Product Overview

Product Name	Brigimadlin (Synonyms: BI 907828)
CAS	2095116-40-6
Formula	C31H25Cl2FN4O3
MW	591.46
Appearance	White to off-white powder
Storage condition	Store short-term at 0-4°C or long-term at -20°C in a dry, dark place.

Product details

Brigimadlin (BI 907828) is a potent, orally active MDM2-p53 antagonist that inhibits the E3 ubiquitin-protein ligase MDM2, thereby preventing its negative regulation of the tumor suppressor p53. It's used in research for metastatic bile duct cancer, pancreatic cancer, lung adenocarcinoma, and bladder cancer.

Related literature

BI-907828, a novel potent MDM2 inhibitor, inhibits glioblastoma brain tumor stem cells in vitro and prolongs survival in orthotopic xenograft mouse models.

PMID: 36521007 PMCID: PMC10158121 DOI: 10.1093/neuonc/noac271

Brightline-2: a phase IIa/IIb trial of brigimadlin (BI 907828) in advanced biliary tract cancer, pancreatic ductal adenocarcinoma or other solid tumors.

PMID: 38214149 DOI: 10.2217/fon-2023-0963

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History

CL3062

Brigimadlin (Synonyms: BI 907828)

2095116-40-6 98+%

Brigimadlin (Synonyms: BI 907828)

Chemical safety data sheet(MSDS)