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Golvatinib | E-7050

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Catalog No：CL3074 CAS No.：928037-13-2 MDLNo： Formula：C33H37F2N7O4 MW：633.69

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Size	Availability	Price(USD)	VIP Price (USD)	Quantity
5 mg	3-5days	$40.00	Visible after login	- +
10 mg	3-5days	$56.00	Visible after login	- +
25 mg	3-5days	$96.00	Visible after login	- +
50 mg	3-5days	$126.00	Visible after login	- +

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Product Overview

Product Name	Golvatinib \| E-7050
CAS	928037-13-2
Formula	C33H37F2N7O4
MW	633.69
Appearance	White to off-white powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Golvatinib (E-7050) is a potent dual inhibitor of both c-Met and VEGFR2 kinases with IC₅₀s of 14 and 16 nM, respectively.

Related literature

E7050: a dual c-Met and VEGFR-2 tyrosine kinase inhibitor promotes tumor regression and prolongs survival in mouse xenograft models.

PMID: 19832844 PMCID: PMC11159146 DOI: 10.1111/j.1349-7006.2009.01343.x

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Met kinase inhibitor E7050 reverses three different mechanisms of hepatocyte growth factor-induced tyrosine kinase inhibitor resistance in EGFR mutant lung cancer.

PMID: 22317763 DOI: 10.1158/1078-0432.CCR-11-1171

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