MK-2206 dihydrochloride | MK-2206 ·2HCl

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Size

Availability

Price(USD)

VIP Price (USD)

Quantity

There is no price information at the moment, you can send an inquiry,and we will reply to you as soon as possible.

Product Overview

Product Name	MK-2206 dihydrochloride \| MK-2206 ·2HCl
CAS	1032350-13-2
Formula	C25H23N5O· 2HCl
MW	482.40
MDL	MFCD14584463
Appearance	Yellow powder
Storage condition	4°C, sealed storage, away from moisture

Product details

MK-2206 dihydrochloride (MK-2206 (2HCl)) is an orally active, BBB-penetrated allosteric AKT inhibitor with IC₅₀s of 5 nM, 12 nM, and 65 nM for AKT1, AKT2, and AKT3, respectively. MK-2206 dihydrochloride induces autophagy.

Related literature

Effects of an oral allosteric AKT inhibitor (MK-2206) on human nasopharyngeal cancer in vitro and in vivo.

PMID: 25336925 PMCID: PMC4199975 DOI: 10.2147/DDDT.S67961

Akt inhibitor MK-2206 promotes anti-tumor activity and cell death by modulation of AIF and Ezrin in colorectal cancer.

PMID: 24581231 PMCID: PMC3941258 DOI: 10.1186/1471-2407-14-145

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History

MK-2206 dihydrochloride | MK-2206 ·2HCl

1032350-13-2 98+%

MK-2206 dihydrochloride | MK-2206 ·2HCl

Chemical safety data sheet(MSDS)