Lercanidipine; CAS: 100427-26-7

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Availability

Price(USD)

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Product Overview

Product Name	Lercanidipine
CAS	100427-26-7
Formula	C36H41N3O6
MW	611.73
MDL	MFCD00867978
Storage condition	4°C, protect from light

Product details

Lercanidipine, a third-generation dihydropyridine calcium channel blocker, exhibits a pIC50 of 7.74 and features lipophilicity, brain penetration, and vascular selectivity . It demonstrates sustained antihypertensive effects, along with reno- and neuroprotection, and possesses antioxidant, anti-inflammatory, and anti-apoptotic properties, making it relevant for cardiovascular and neurological research.

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Lercanidipine and labedipinedilol--A attenuate lipopolysaccharide/interferon-γ-induced inflammation in rat vascular smooth muscle cells through inhibition of HMGB1 release and MMP-2, 9 activities.

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