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Product Overview

Product Name	Anti-Human CD3xGPRC5D Bispecific Antibody ( Talquetamab； JNJ-64407564； JNJ-7564)
CAS	2226212-40-2
Storage condition	store at -20°C \| Avoid repeated freeze-thaw.

Product details

Talquetamab is a first-in-class bispecific antibody targeting GPRC5D and CD3, designed to recruit and activate T cells to eliminate GPRC5D-positive multiple myeloma cells. Talquetamab (JNJ-64407564) has antitumor activity.

Related literature

Preclinical activity and determinants of response of the GPRC5DxCD3 bispecific antibody talquetamab in multiple myeloma.

PMID: 33890981 PMCID: PMC8095149 DOI: 10.1182/bloodadvances.2020003805

A T-cell-redirecting bispecific G-protein-coupled receptor class 5 member D x CD3 antibody to treat multiple myeloma.

PMID: 32040549 PMCID: PMC7146017 DOI: 10.1182/blood.2019003342

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History

CLA1634

Anti-Human CD3xGPRC5D Bispecific Antibody ( Talquetamab； JNJ-64407564； JNJ-7564)

2226212-40-2 95+%