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Product Overview

Product Name	Anti-Human PD-1xCTLA-4 Bispecific Antibody(Vudalimab；XmAb-20717,cytotoxic T-lymphocyte-associated protein 4, CD152;programmed cell death 1, PD1, PD-1, CD279)
CAS	2329669-72-7
Storage condition	Avoid repeated freeze-thaw. -80°C for one-year storage.

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Product details

Vudalimab is a fully humanized bispecific antibody that potently inhibits both PD-1 and CTLA-4, key immune checkpoint receptors. It is designed to selectively activate tumor-targeting T cells, enhancing the immune response against cancer.

Related literature

June Hou, et, al. 733 A phase 2 study of vudalimab (XmAb®20717), an anti-PD-1/CTLA-4 bispecific antibody, in patients with selected gynecological malignancies and high-risk metastatic castration-resistant prostate-cancer.

https://doi.org/10.1136/jitc-2022-SITC2022.0733

History

CLA1666

Anti-Human PD-1xCTLA-4 Bispecific Antibody(Vudalimab；XmAb-20717,cytotoxic T-lymphocyte-associated protein 4, CD152;programmed cell death 1, PD1, PD-1, CD279)

2329669-72-7 95+%