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Product Overview

Product Name	Anti-Human Her2 (Trastuzumab Deruxtecan; T-DXd)
CAS	1826843-81-5
Storage condition	store at -20°C

Product details

Trastuzumab Deruxtecan (Enhertu) is a HER2-targeting ADC combining a humanized anti-HER2 antibody with a topoisomerase I inhibitor, deruxtecan (DXd). Trastuzumab deruxtecan can be used for the research of HER2-positive breast cancer and gastric cancer.

Related literature

Trastuzumab deruxtecan for the treatment of patients with HER2-positive gastric cancer.

PMID: 33473250 PMCID: PMC7797586 DOI: 10.1177/1758835920986518

Interstitial pneumonitis related to trastuzumab deruxtecan, a human epidermal growth factor receptor 2-targeting Ab-drug conjugate, in monkeys.

Cancer Sci. 2020 Dec;111(12):4636-4645.

[Fam-] trastuzumab deruxtecan (DS-8201a)-induced antitumor immunity is facilitated by the anti-CTLA-4 antibody in a mouse model.

PMID: 31574081 PMCID: PMC6772042 DOI: 10.1371/journal.pone.0222280

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