Protopine

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Size

Availability

Price(USD)

VIP Price (USD)

Quantity

There is no price information at the moment, you can send an inquiry,and we will reply to you as soon as possible.

Product Overview

Product Name	Protopine
CAS	130-86-9
Formula	C20H19NO5
MW	353.37
Appearance	White to off-white powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Protopine (Corydinine), an isoquinoline alkaloid, is a specific reversible and competitive inhibitor of acetylcholinesterase. Protopine exhibits anti-inflammation, anti-microbial, anti-angiogenic and anti-tumour activity.

Related literature

Protopine from Corydalis ternata has anticholinesterase and antiamnesic activities.

PMID: 10232064 DOI: 10.1055/s-1999-13983

Protopine triggers apoptosis via the intrinsic pathway and regulation of ROS/PI3K/Akt signalling pathway in liver carcinoma.

PMID: 34315493 PMCID: PMC8314675 DOI: 10.1186/s12935-021-02105-5

Protopine inhibits serotonin transporter and noradrenaline transporter and has the antidepressant-like effect in mice models.

PMID: 16530230 DOI: 10.1016/j.neuropharm.2006.01.003

Protective effect of protopine on the focal cerebral ischaemic injury in rats.

Basic Clin Pharmacol Toxicol. 2007 Aug;101(2):85-9.

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History

HL1332