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PD184352(CI-1040)

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Catalog No:CL2485 CAS No.:212631-79-3 MDLNo: Formula:C17H14ClF2 IN2O2 MW:478.66
Size Availability Price(USD) VIP Price (USD) Quantity
5 mg 3-5days $100.00 Visible after login
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10 mg 3-5days $160.00 Visible after login
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25 mg 3-5days $290.00 Visible after login
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Product Overview
Product Name PD184352(CI-1040)
CAS212631-79-3
FormulaC17H14ClF2 IN2O2
MW478.66
AppearanceWhite to off-white powder
Storage condition Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Product details

PD184352 (PD-184352; CI-1040), an analog of benzhydroxamate, is an orally bioactive, specific, allosteric/non-ATP competitive MEK1/2 inhibitor with potential anticancer activity. In cell-based assays, it inhibits MEK1/2 with IC50 values of 17 nM and exhibits a 100-fold preference for MEK1/2 over MEK5. In mouse xenograft models, it exhibits strong in vitro anti-proliferative activity and significant in vivo antitumor efficacy.

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