CaCCinh-A01 | TMEM16 Blocker I

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
5 mg	In-stock	$400.00	Visible after login	- +
10 mg	3-5days	$600.00	Visible after login	- +
25 mg	3-5days	$1100.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

5 mg

In-stock

$400.00

Visible after login

- +

10 mg

3-5days

$600.00

Visible after login

- +

25 mg

3-5days

$1100.00

Visible after login

- +

Product Overview

Product Name	CaCCinh-A01 (Synonyms: TMEM16 Blocker I)
CAS	407587-33-1
Formula	C18H21NO4S
MW	347.43
Appearance	White to off-white powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

CaCCinh-A01 (TMEM16 Blocker I) is a blocker of TMEM16A with IC50 of 2.1 μM. CaCCinh-A01 is also an inhibitor of calcium-activated chloride channel (CaCC) with IC50 of ~ 10 μM.
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Related literature

TMEM16A inhibitors reveal TMEM16A as a minor component of calcium-activated chloridechannel conductance in airway and intestinal epithelial cells.

PMID: 21084298 PMCID: PMC3023530 DOI: 10.1074/jbc.M110.175109

Small-molecule screen identifies inhibitors of a human intestinal calcium-activated chloridechannel.

PMID: 18083779 DOI: 10.1124/mol.107.043208

TMEM16A Inhibition Preserves Blood-Brain Barrier Integrity After Ischemic Stroke.

PMID: 31447648 PMCID: PMC6691060 DOI: 10.3389/fncel.2019.00360

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History

CL1096

CaCCinh-A01 (Synonyms: TMEM16 Blocker I)

407587-33-1 98+%

CaCCinh-A01 (Synonyms: TMEM16 Blocker I)

Chemical safety data sheet(MSDS)

Certificate Of Authenticity(CPA)