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Apatinib | Apatinib Free base | YN968D1| Rivoceranib

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Catalog No：CL2507 CAS No.：811803-05-1 MDLNo： Formula：C24H23N5O MW：397.47

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Size	Availability	Price(USD)	VIP Price (USD)	Quantity
1 mg	In-stock	$148.00	Visible after login	- +
5 mg	In-stock	$288.00	Visible after login	- +

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Product Overview

Product Name	Apatinib \| Apatinib Free base \| YN968D1\| Rivoceranib
CAS	811803-05-1
Formula	C24H23N5O
MW	397.47
Storage condition	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

Product details

Apatinib (Rivoceranib, YN968D1) is a potent inhibitor of the VEGF signaling pathway with IC50 values of 1 nM, 13 nM, 429 nM and 530 nM for VEGFR-2, Ret (c-Ret), c-Kit and c-Src, respectively. Apatinib induces both autophagy and apoptosis.

Related literature

YN968D1 is a novel and selective inhibitor of vascular endothelial growth factor receptor-2 tyrosine kinase with potent activity in vitro and in vivo.

PMID: 21443688 PMCID: PMC11158267 DOI: 10.1111/j.1349-7006.2011.01939.x

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Apatinib | Apatinib Free base | YN968D1| Rivoceranib

811803-05-1 98+%