Laduviglusib monohydrochloride | CHIR-99021 Monohydrochloride

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Availability

Price(USD)

VIP Price (USD)

Quantity

There is no price information at the moment, you can send an inquiry,and we will reply to you as soon as possible.

Product Overview

Product Name	Laduviglusib monohydrochloride \| CHIR-99021 Monohydrochloride \| T99021 Monohydrochloride
CAS	1797989-42-4
Formula	C22H18Cl2N8·HCl
MW	501.80
Appearance	White to yellow powder
Storage condition	4°C, sealed storage, away from moisture

Product details

Laduviglusib (CHIR-99021) monohydrochloride is a potent and selective GSK-3α/β inhibitor with IC50s of 10 nM and 6.7 nM. Laduviglusib monohydrochloride shows >500-fold selectivity for GSK-3 over CDC2, ERK2 and other protein kinases. Laduviglusib monohydrochloride is also a potent Wnt/β-catenin signaling pathway activator. Laduviglusib monohydrochloride enhances mouse and human embryonic stem cells self-renewal. Laduviglusib monohydrochloride induces autophagy.

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