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Calcitriol (1,25-Dihydroxyvitamin D3)

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Catalog No：CL1100 CAS No.：32222-06-3 MDLNo：MFCD00867079 Formula：C27H44O3 MW：416.64

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Product Overview
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Product details
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Product Overview

Product Name	Calcitriol (1,25-Dihydroxyvitamin D3)
CAS	32222-06-3
Formula	C27H44O3
MW	416.64
MDL	MFCD00867079
Appearance	White to off-white powder
Storage condition	-20°C, protect from light, stored under nitrogen

Product details

Calcitriol is a nonselective vitamin D receptor activator/agonist(VDRA), exhibiting a 10-fold higher vitamin D receptor (VDR) binding affinity(IC50=0.4 nM) than the selective VDRA paricalcitol.

Solutions are unstable and should be fresh-prepared.

Related literature

Beneficial effects of calcitriol on hypertension, glucose intolerance, impairment of endothelium-dependent vascular relaxation, and visceral adiposity in fructose-fed hypertensive rats.

PMID: 25774877 PMCID: PMC4361671 DOI: 10.1371/journal.pone.0119843

Calcitriol restores antiestrogen responsiveness in estrogen receptor negative breast cancer cells: a potential new therapeutic approach.

PMID: 24678876 PMCID: PMC3972996 DOI: 10.1186/1471-2407-14-230

Calcitriol Inhibits Cervical Cancer Cell Proliferation Through Downregulation of HCCR1 Expression.

PMID: 26629942 PMCID: PMC7842578 DOI: 10.3727/096504015X14424348425991