Redafamdastat | PF-04457845 | PF-4457845

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
5 mg	3-5days	$66.00	Visible after login	- +
10 mg	3-5days	$116.00	Visible after login	- +
25 mg	3-5days	$216.00	Visible after login	- +
50 mg	3-5days	$326.00	Visible after login	- +
100 mg	3-5days	$546.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

5 mg

3-5days

$66.00

Visible after login

- +

10 mg

3-5days

$116.00

Visible after login

- +

25 mg

3-5days

$216.00

Visible after login

- +

50 mg

3-5days

$326.00

Visible after login

- +

100 mg

3-5days

$546.00

Visible after login

- +

Product Overview

Product Name	Redafamdastat \| PF-04457845 \| PF-4457845
CAS	1020315-31-4
Formula	C23H20F3N5O2
MW	455.43
Appearance	White to off-white powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Redafamdastat (PF-04457845) is a highly efficacious and selective FAAH inhibitor with IC₅₀ values is 7.2±0.63 nM and 7.4±0.62 nM for hFAAH and rFAAH, respectively.

Related literature

Discovery of PF-04457845: A Highly Potent, Orally Bioavailable, and Selective Urea FAAH Inhibitor.

PMID: 21666860 PMCID: PMC3109749 DOI: 10.1021/ml100190t

Inhibition of Endocannabinoid-Metabolizing Enzymes in Peripheral Tissues Following Developmental Chlorpyrifos Exposure in Rats.

PMID: 28820005 PMCID: PMC5585048 DOI: 10.1177/1091581817725272

Mechanistic and pharmacological characterization of PF-04457845: a highly potent and selective fatty acid amide hydrolase inhibitor that reduces inflammatory and noninflammatory pain.

PMID: 21505060 PMCID: PMC3126636 DOI: 10.1124/jpet.111.180257

Sorry, no related items

History

CL1240

Redafamdastat | PF-04457845 | PF-4457845

1020315-31-4 98+%