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Ulixertinib (Synonyms: BVD-523; VRT752271)

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Catalog No：CL1281 CAS No.：869886-67-9 MDLNo： Formula：C21H22Cl2N4O2 MW：433.33

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Product Overview

Product Name	Ulixertinib (Synonyms: BVD-523; VRT752271)
CAS	869886-67-9
Formula	C21H22Cl2N4O2
MW	433.33

Product details

Ulixertinib (BVD-523; VRT752271) is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC50 of <0.3 nM against ERK2. Ulixertinib (BVD-523; VRT752271) inhibits the phosphorylated ERK2 (pERK) and downstream kinase RSK (pRSK) in an A375 melanoma cell line.

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CL1281A

Ulixertinib hydrochloride (Synonyms: BVD-523 hydrochloride; VRT752271 hydrochloride;Ulixertinib HCl salt) ; (S)-4-(5-chloro-2-(isopropylamino)pyridin-4-yl)-N-(1-(3-chlorophenyl)-2-hydroxyethyl)-1H-pyrrole-2-carboxamide hydrochloride.

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CL1281

Ulixertinib (Synonyms: BVD-523; VRT752271)

869886-67-9 98+%