Trabectedin (Ecteinascidin 743; ET-743) supplier | purchase Trabectedin | Trabectedin cost | Trabectedin (Ecteinascidin 743; ET-743) manufacturer | order Trabectedin

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
1 mg	3-5days	$266.00	Visible after login	- +
5 mg	3-5days	$518.00	Visible after login	- +

Product Overview

Product Name	Trabectedin (Synonyms: Ecteinascidin 743; ET-743)
CAS	114899-77-3
Formula	C39H43N3O11S
MW	761.84
Appearance	White to light yellow powder
Storage condition	-20°C, protect from light, stored under nitrogen

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Product details

Trabectedin (Ecteinascidin 743; ET-743) is a tetrahydroisoquinoline alkaloid with potent antitumor activity. Trabectedin binds to the minor groove of DNA, blocks transcription of stress-induced proteins, induces DNA backbone cleavage and cancer cells apoptosis, and increases the generation of ROS in MCF-7 and MDA-MB-453 cells. Trabectedin has the potential for soft tissue sarcoma and ovarian cancer research.
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Related literature

A diverse induction of apoptosis by trabectedin in MCF-7 (HER2-/ER+) and MDA-MB-453 (HER2+/ER-) breast cancer cells. Toxicol Lett.

PMID: 23792433 DOI: 10.1016/j.toxlet.2013.06.213

Trabectedin (Synonyms: Ecteinascidin 743; ET-743)

Chemical safety data sheet(MSDS)