Axitinib | AG-013736 | CAS 319460-85-0

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
100 mg	In-stock	$148.00	Visible after login	- +
200 mg	In-stock	$238.00	Visible after login	- +
500 mg	In-stock	$398.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

100 mg

In-stock

$148.00

Visible after login

- +

200 mg

In-stock

$238.00

Visible after login

- +

500 mg

In-stock

$398.00

Visible after login

- +

Product Overview

Product Name	Axitinib \| AG-013736
CAS	319460-85-0
Formula	C22H18N4OS
MW	386.47
Appearance	White to light yellow powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Axitinib (formerly AG013736; brand name Inlyta), is a potent, orally bioavailable, small molecule that inhibits multiple kinases and has the potential to treat cancer. In porcine aorta endothelial cells, it inhibits several kinases, including PDGFRβ, VEGFR1, VEGFR2, VEGFR3, and c-Kit, with IC50 values of 0.1 nM, 0.2 nM, 0.1-0.3 nM, 1.6 nM, and 1.7 nM, respectively. Axitinib has an anti-angiogenic effect by inhibiting the proangiogenic cytokines PDGF and VEGF.

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History

CL1637

Axitinib | AG-013736

319460-85-0 98+%