Fenretinide (Synonyms: 4-HPR; 维甲酰酚胺; 芬维A胺;酚维A胺); CAS : 65646-68-6

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Product Overview

Product Name	Fenretinide (Synonyms: 4-HPR; 维甲酰酚胺; 芬维A胺;酚维A胺)
CAS	65646-68-6
Formula	C26H33NO2
MW	391.55
MDL	MFCD00792674
Appearance	Light yellow to yellow powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Fenretinide (4-HPR) is a synthetic retinoid deriverative, binding to the retinoic acid receptors (RAR) at concentrations necessary to induce cell death.

Related literature

Fenretinide Prevents Lipid-induced Insulin Resistance by Blocking Ceramide Biosynthesis.

PMID: 22474281 PMCID: PMC3366851 DOI: 10.1074/jbc.M112.359950

Dihydroceramide accumulation and reactive oxygen species are distinct and nonessential events in 4-HPR-mediated leukemia cell death.

PMID: 22428532 PMCID: PMC3663831 DOI: 10.1139/o2012-001

Fenretinide metabolism in humans and mice: utilizing pharmacological modulation of its metabolic pathway to increase systemic exposure.

PMID: 21391977 PMCID: PMC3144539 DOI: 10.1111/j.1476-5381.2011.01310.x

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