Eribulin | B1939 | E7389 | ER-086526 | 253128-41-5 |艾日布林

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Size

Availability

Price(USD)

VIP Price (USD)

Quantity

There is no price information at the moment, you can send an inquiry,and we will reply to you as soon as possible.

Product Overview

Product Name	Eribulin \| B1939 \| E7389 \| ER-086526
CAS	253128-41-5
Formula	C40H59NO11
MW	729.90
Appearance	White to off-white powder
Storage condition	-20°C, protect from light, stored under nitrogen

Product details

Eribulin (E7389) is a microtubule targeting agent that is used for the research of metastatic breast cancer. Eribulin inhibits the proliferation of cancer cells by binding microtubule proteins and microtubules.

Related literature

Inhibition of centromere dynamics by eribulin (E7389) during mitotic metaphase.

PMID: 18645010 PMCID: PMC2562299 DOI: 10.1158/1535-7163.MCT-08-0095

Eribulin binds at microtubule ends to a single site on tubulin to suppress dynamic instability.

PMID: 20030375 PMCID: PMC2846717 DOI: 10.1021/bi901810u

Low-dose eribulin reduces lung metastasis of osteosarcoma in vitro and in vivo.

PMID: 30719211 PMCID: PMC6349434 DOI: 10.18632/oncotarget.26536

Eribulin induces irreversible mitotic blockade: implications of cell-based pharmacodynamics for in vivo efficacy under intermittent dosing conditions.

PMID: 21127197 DOI: 10.1158/0008-5472.CAN-10-1874