Vatalanib Dihydrochloride | Vatalanib 2HCl |CAS 212141-51-0

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
20 mg	In-stock	$56.00	Visible after login	- +
50 mg	In-stock	$63.00	Visible after login	- +
100 mg	In-stock	$86.00	Visible after login	- +

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20 mg

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$56.00

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50 mg

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100 mg

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Product Overview

Product Name	Vatalanib Dihydrochloride (Synonyms: PTK787 dihydrochloride; ZK-222584 dihydrochloride; CGP-797870 dihydrochloride;Vatalanib 2HCl)
CAS	212141-51-0
Formula	C20H17Cl3N4
MW	419.73
Appearance	Off-white to pink powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Vatalanib (PTK787 or ZK-222584, cpg-79787 2HCl) 2HCl is a novel, potent and orally bioavailable inhibitor of VEGFR2/KDR with potential anticancer activity. In a cell-free experiment, it inhibits VEGFR2/KDR with an IC50 of 37 nM, is less effective against VEGFR1/Flt-1, and is 18-fold more potent against VEGFR3/Flt-4. With strong anti-proliferative activity in vitro and strong antitumor efficaciousness in vivo, it is an anilinophthalazine analog. The protein kinase domains of VEGFR 1 and 2 are bound by vatalanib, which then inhibits them. The PDGF receptor, c-Kit, and c-Fms are among the related receptor tyrosine kinases that this agent binds to and inhibits.
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History

CL1906

Vatalanib Dihydrochloride (Synonyms: PTK787 dihydrochloride; ZK-222584 dihydrochloride; CGP-797870 dihydrochloride;Vatalanib 2HCl)

212141-51-0 98+%

Vatalanib Dihydrochloride (Synonyms: PTK787 dihydrochloride; ZK-222584 dihydrochloride; CGP-797870 dihydrochloride;Vatalanib 2HCl)

Chemical safety data sheet(MSDS)

Certificate Of Authenticity(CPA)