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Ciclesonide (RPR251526)

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Catalog No：CL1968 CAS No.：126544-47-6 MDLNo： Formula：C32H44O7 MW：540.69

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Size	Availability	Price(USD)	VIP Price (USD)	Quantity
5 mg	In-stock	$220.00	Visible after login	- +
10 mg	In-stock	$350.00	Visible after login	- +
25 mg	In-stock	$550.00	Visible after login	- +
50 mg	In-stock	$860.00	Visible after login	- +

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Product Overview

Product Name	Ciclesonide (RPR251526)
CAS	126544-47-6
Formula	C32H44O7
MW	540.69
Appearance	White-like crystalline powder

Product details

Ciclesonide (CIC) is a prodrug form of the glucocorticoid receptor agonist desisobutyryl-CIC (des-CIC). CIC binds to the glucocorticoid receptor with a Ki value of 37 nM. It is selective for the glucocorticoid receptor over the estrogen, progesterone, and testosterone receptors. CIC inhibits eosinophil influx into the lung (ED50 = 0.49 mg/kg) and reduces sephadex-induced lung edema (ED50 = 0.72 mg/kg) in a rat model of ovalbumin-sensitized and -challenged airway inflammation. Formulations containing CIC have been used in the maintenance treatment of asthma and in the treatment of allergic rhinitis.

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CL1968

Ciclesonide (RPR251526)

126544-47-6 98+%