Nepicastat HCl (SYN-117; SYN 117;RS-25560-197; RS 25560-197), the hydrochloride salt ofNepicastat, is a potent and selective inhibitor of dopamine-β-hydroxylase (an enzyme that catalyzes the conversion of dopamine to norepinephrine) with the potential to treat CHF-congestive heart failure.
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