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PD184352(Synonyms: CI-1040)

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Catalog No：CL2485 CAS No.：212631-79-3 MDLNo：MFCD02683961 Formula：C17H14ClF2 IN2O2 MW：478.66

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Size	Availability	Price(USD)	VIP Price (USD)	Quantity
5 mg	3-5days	$100.00	Visible after login	- +
10 mg	3-5days	$160.00	Visible after login	- +
25 mg	3-5days	$290.00	Visible after login	- +

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Product Overview

Product Name	PD184352(Synonyms: CI-1040)
CAS	212631-79-3
Formula	C17H14ClF2 IN2O2
MW	478.66
MDL	MFCD02683961
Appearance	White to off-white powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

PD184352 (PD-184352; CI-1040), an analog of benzhydroxamate, is an orally bioactive, specific, allosteric/non-ATP competitive MEK1/2 inhibitor with potential anticancer activity. In cell-based assays, it inhibits MEK1/2 with IC50 values of 17 nM and exhibits a 100-fold preference for MEK1/2 over MEK5. In mouse xenograft models, it exhibits strong in vitro anti-proliferative activity and significant in vivo antitumor efficacy.

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