Torin 2

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
5 mg	3-5days	$150.00	Visible after login	- +
10 mg	3-5days	$225.00	Visible after login	- +
25 mg	3-5days	$415.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

5 mg

3-5days

$150.00

Visible after login

- +

10 mg

3-5days

$225.00

Visible after login

- +

25 mg

3-5days

$415.00

Visible after login

- +

Product Overview

Product Name	Torin 2
CAS	1223001-51-1
Formula	C24H15F3N4O
MW	432.40
Appearance	White to light yellow powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Torin-2 is a novel, second-generation ATP-competitive inhibitor that is potent and selective for mTOR with a superior pharmacokinetic profile to previous inhibitors ((EC50 = 0.3 nM). It has been shown that Torin-2 displayed dramatic antiproliferative activity across a panel of cancer cell lines. Torin-2 showed a powerful cytotoxic activity, inhibiting the growth of each cell line in a dose-dependent manner, with an IC₅₀ in the nanomolar range. Torin-2 caused both apoptosis and autophagy, induced cell cycle arrest in G₀/G₁ phase and affected both mTORC1 and mTORC2 activities.

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