| Product Name | AdipoRon (Synonyms: SC-396658) |
|---|---|
| CAS | 924416-43-3 |
| Formula | C27H28N2O3 |
| MW | 428.52 |
| Appearance | Off-white to light yellow powder |
| Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
| Size | Availability | Price(USD) | VIP Price (USD) | Quantity |
|---|---|---|---|---|
| 10 mg | 3-5days | $120.00 | Visible after login | |
| 50 mg | 3-5days | $338.00 | Visible after login | |
| 25 mg | 3-5days | $720.00 | Visible after login |
| Product Name | AdipoRon (Synonyms: SC-396658) |
|---|---|
| CAS | 924416-43-3 |
| Formula | C27H28N2O3 |
| MW | 428.52 |
| Appearance | Off-white to light yellow powder |
| Storage condition | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
AdipoRon (also known as SC-396658) is a novel, first-in-class, and orally bioavailable adiponectin receptor agonist with KD of 1.8 and 3.1 μM for AdipoR1 and AdipoR2, respectively. AdipoRon (5-50 μM) increased AMPK phosphorylation via AdipoR1 in a dose-dependent way. Also, AdipoRon replenished adiponectin-stimulated AMPK phosphorylation. In C2C12 myotubes, AdipoRon increased PGC-1α expression and mitochondrial DNA content in a Ca2+- and dose-dependent way.
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