NVP-BEZ235 | Dactolisib | BEZ235

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Availability

Price(USD)

VIP Price (USD)

Quantity

There is no price information at the moment, you can send an inquiry,and we will reply to you as soon as possible.

Product Overview

Product Name	NVP-BEZ235 (Synonyms: Dactolisib; BEZ235)
CAS	915019-65-7
Formula	C30H23N5O
MW	469.54
MDL	MFCD10565944
Appearance	White to light yellow powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR, with IC50 values of 4 nM for p110α, 5 nM for p110γ, 7 nM for p110δ, 75 nM for p110β, and 20.7 nM for mTOR.

Related literature

Targeting PI3K/mTOR Signaling Displays Potent Antitumor Efficacy against Nonfunctioning Pituitary Adenomas.

https://doi.org/10.1158/1078-0432.CCR-15-0288

Effects of the dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235 on the tumor vasculature: implications for clinical imaging.

https://doi.org/10.1158/0008-5472.CAN-08-1044

Sorry, no related items

History

CL2601

NVP-BEZ235 (Synonyms: Dactolisib; BEZ235)

915019-65-7 98+%

CL3055

Troxacitabine (Synonyms: BCH 4556; L-OddC; SPD 758)

145918-75-8 98+%

NVP-BEZ235 (Synonyms: Dactolisib; BEZ235)

Chemical safety data sheet(MSDS)