Imrecoxib

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Availability

Price(USD)

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Quantity

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Product Overview

Product Name	Imrecoxib
CAS	395683-14-4
Formula	C21H23NO3S
MW	369.48
Appearance	White to off-white powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Imrecoxib, also known as BAP-909, a novel and selective cyclooxygenase 2 inhibitor with anti-inflammatory effect. Imrecoxib was found to inhibit COX-1 and COX-2 with IC50 value of 115+/-28 nmol/L and 18+/-4 nmol/L, respectively. Imrecoxib was shown to selectively and dose-dependently inhibit COX-2 mRNA level. Imrecoxib effectively inhibited carrageenan-induced acute inflammation at the doses of 5, 10, and 20 mg/kg i.g. and adjuvant-induced chronic inflammation at the doses of 10 and 20 mg/kg/d i.g.

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