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Fasiglifam | TAK-875

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Catalog No：CL2854 CAS No.：1000413-72-8 MDLNo： Formula：C29H32O7S MW：524.63

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Size	Availability	Price(USD)	VIP Price (USD)	Quantity
2 mg	3-5days	$76.00	Visible after login	- +
5 mg	3-5days	$126.00	Visible after login	- +
10 mg	3-5days	$216.00	Visible after login	- +

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Product Overview

Product Name	Fasiglifam \| TAK-875
CAS	1000413-72-8
Formula	C29H32O7S
MW	524.63
Appearance	White to off-white powder
Storage condition	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

Product details

Fasiglifam (TAK-875) is a potent, selective and orally bioavailable GPR40 agonist with EC₅₀ of 72 nM.

Related literature

TAK-875, an orally available G protein-coupled receptor 40/free fatty acid receptor 1 agonist, enhances glucose-dependent insulin secretion and improves both postprandial and fasting hyperglycemia in type 2 diabetic rats.

PMID: 21752941 DOI: 10.1124/jpet.111.183772

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17,18-EpETE-GPR40 axis ameliorates contact hypersensitivity by inhibiting neutrophil mobility in mice and cynomolgus macaques.

PMID: 29288079 DOI: 10.1016/j.jaci.2017.09.053

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