Product Name | Rosiglitazone HCl | BRL 49653 hydrochloride |
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CAS | 302543-62-0 |
Formula | C18H19N3O3S·HCl |
MW | 393.89 | 357.43 (free) |
Appearance | White to off-white powder |
Storage condition | -20°C, sealed storage, away from moisture |
Size | Availability | Price(USD) | VIP Price (USD) | Quantity | |
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Product Name | Rosiglitazone HCl | BRL 49653 hydrochloride |
---|---|
CAS | 302543-62-0 |
Formula | C18H19N3O3S·HCl |
MW | 393.89 | 357.43 (free) |
Appearance | White to off-white powder |
Storage condition | -20°C, sealed storage, away from moisture |
Rosiglitazone (BRL 49653) hydrochloride is an orally active selective PPARγ agonist (EC50: 60 nM, Kd: 40 nM). Rosiglitazone hydrochloride is a TRPC5 activator (EC50: 30 μM) and TRPM3 inhibitor. Rosiglitazone hydrochloride can be used in the research of obesity and diabetes, senescence, ovarian cancer.
PMID: 21406603 PMCID: PMC3102547 DOI: 10.1124/mol.110.069922
Beneficial effects of rosiglitazone and losartan combination in diabetic rats.
PMID: 28892640 DOI: 10.1139/cjpp-2017-0332
PMID: 34182323 DOI: 10.1016/j.intimp.2021.107809
Rosiglitazone ameliorates senescence and promotes apoptosis in ovarian cancer induced by olaparib.
PMID: 34182323 DOI: 10.1016/j.intimp.2021.107809