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Lanifibranor (IVA337)

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Catalog No：CL2939 CAS No.：927961-18-0 MDLNo： Formula：C19H15ClN2O4S2 MW：434.92

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Size	Availability	Price(USD)	VIP Price (USD)	Quantity
5 mg	3-5days	$128.00	Visible after login	- +
10 mg	3-5days	$236.00	Visible after login	- +

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Product Overview

Product Name	Lanifibranor (IVA337)
CAS	927961-18-0
Formula	C19H15ClN2O4S2
MW	434.92
Appearance	White to light brown powder
Storage condition	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

Product details

Lanifibranor is a pan peroxisome proliferator-activated receptor (PPAR) agonist with EC₅₀s of 1.5, 0.87 and 0.21 μM for human PPARα, PPARσ and PPARγ, respectively.

Related literature

Design, Synthesis, and Evaluation of a Novel Series of Indole Sulfonamide Peroxisome Proliferator Activated Receptor (PPAR) α/γ/δ Triple Activators: Discovery of Lanifibranor, a New Antifibrotic Clinical Candidate.

J Med Chem. 2018 Feb 27.

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Pan PPAR agonist IVA337 is effective in prevention and treatment of experimental skin fibrosis.

PMID: 26961294 PMCID: PMC5136696 DOI: 10.1136/annrheumdis-2015-208029

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