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SNS-314

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Catalog No：CL2957 CAS No.：1057249-41-8 MDLNo： Formula：C18H15Cl N6OS2 MW：430.93

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Product Overview

Product Name	SNS-314
CAS	1057249-41-8
Formula	C18H15Cl N6OS2
MW	430.93
Storage condition	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

Product details

SNS-314 is a potent and selective aurora kinase inhibitor with IC₅₀s of 9, 31, and 6 nM for aurora A, B and C, respectively.

Related literature

Discovery of a potent and selective aurora kinase inhibitor.

PMID: 18678489 DOI: 10.1016/j.bmcl.2008.07.073

SNS-314, a pan-Aurora kinase inhibitor, shows potent anti-tumor activity and dosing flexibility in vivo.

PMID: 19649632 DOI: 10.1007/s00280-009-1076-8

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