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Tovinontrine (Synonyms: IMR-687)

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Catalog No：CL3063 CAS No.：2062661-53-2 MDLNo：MFCD34567171 Formula：C21H26N6O2 MW：394.47

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Size	Availability	Price(USD)	VIP Price (USD)	Quantity
1 mg	3-5 days	$206.00	Visible after login	- +
5 mg	3-5 days	$460.00	Visible after login	- +
10 mg	3-5 days	$658.00	Visible after login	- +

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Product Overview

Product Name	Tovinontrine (Synonyms: IMR-687)
CAS	2062661-53-2
Formula	C21H26N6O2
MW	394.47
MDL	MFCD34567171
Appearance	White to off-white powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Tovinontrine (IMR-687) is a highly potent and selective phosphodiesterase-9 (PDE9) inhibitor specifically for the treatment of sickle cell disease. IC₅₀s are 8.19 nM and 9.99 nM for PDE9A1 and PDE9A2, respectively.

Related literature

A novel, highly potent and selective phosphodiesterase-9 inhibitor for the treatment of sickle cell disease. Haematologica.

PMID: 31147439 PMCID: PMC7049346 DOI: 10.3324/haematol.2018.213462

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Tovinontrine (Synonyms: IMR-687)

2062661-53-2 98+%

CL3246

AM580 (Synonyms: CD336; NSC608001; Ro 40-6055)

102121-60-8 98+%