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Danoprevir (Synonyms: R7227; RO5190591; RG7227; ITMN-191;丹诺瑞韦)

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Catalog No：CL3100 CAS No.：850876-88-9 MDLNo：MFCD16038038 Formula：C35H46FN5O9S MW：731.83

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Size	Availability	Price(USD)	VIP Price (USD)	Quantity
1 mg	3-5days	$66.00	Visible after login	- +
5 mg	3-5days	$166.00	Visible after login	- +
10 mg	3-5days	$266.00	Visible after login	- +
25 mg	3-5days	$426.00	Visible after login	- +
50 mg	3-5days	$626.00	Visible after login	- +
100 mg	3-5days	$866.00	Visible after login	- +

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Product Overview

Product Name	Danoprevir (Synonyms: R7227; RO5190591; RG7227; ITMN-191;丹诺瑞韦)
CAS	850876-88-9
Formula	C35H46FN5O9S
MW	731.83
MDL	MFCD16038038
Appearance	White to off-white powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Danoprevir (RG7227) is a peptidomimetic inhibitor of the NS3/4A protease(IC50=0.2-3.5 nM) of hepatitis C virus (HCV).

Related literature

Genotype differences in susceptibility and resistance development of hepatitis C virus to protease inhibitors telaprevir (VX-950) and danoprevir (ITMN-191).

PMID: 21480315 DOI: 10.1002/hep.24172

Read more

Natural prevalence of hepatitis C virus variants with decreased sensitivity to NS3.4A protease inhibitors in treatment-naive subjects.

PMID: 18637752 DOI: 10.1086/591141

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Bardoxolone and bardoxolone methyl, two Nrf2 activators in clinical trials, inhibit SARS-CoV-2 replication and its 3C-like protease.

PMID: 34052830 PMCID: PMC8164054 DOI: 10.1038/s41392-021-00628-x

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