GSK256066;6-[[3-[(Dimethylamino)carbonyl]phenyl]sulfonyl]-4-[(3-methoxyphenyl)amino]-8-methyl-3-quinolinecarboxamide;CAS: 801312-28-7

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
1 mg	3-5 days	$48.00	Visible after login	- +
5 mg	3-5 days	$106.00	Visible after login	- +
10 mg	3-5 days	$166.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

1 mg

3-5 days

$48.00

Visible after login

- +

5 mg

3-5 days

$106.00

Visible after login

- +

10 mg

3-5 days

$166.00

Visible after login

- +

Product Overview

Product Name	GSK256066;6-[[3-[(Dimethylamino)carbonyl]phenyl]sulfonyl]-4-[(3-methoxyphenyl)amino]-8-methyl-3-quinolinecarboxamide
CAS	801312-28-7
Formula	C27H26N4O5S
MW	518.58
MDL	MFCD18206923
Appearance	Light yellow to yellow powder
Storage condition	Store short-term at 0-4°C or long-term at -20°C in a dry, dark place.

Product details

GSK256066 is a selective and high-affinity phosphodiesterase 4 (PDE4) inhibitor, with an IC50 value of 3.2 pM for inhibiting PDE4B. This compound has been developed for research into chronic obstructive pulmonary disease (COPD).

Related literature

GSK256066, an exceptionally high-affinity and selective inhibitor of phosphodiesterase 4 suitable for administration by inhalation: in vitro, kinetic, and in vivo characterization.

PMID: 21205923 DOI: 10.1124/jpet.110.173690

In vivo characterization of GSK256066, a high-affinity inhaled phosphodiesterase 4 inhibitor.

PMID: 21205924 DOI: 10.1124/jpet.110.173641

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