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GW6471

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Catalog No:CL3698 CAS No.:880635-03-0 MDLNo:MFCD07784503 Formula:C35H36F3N3O4 MW:619.67
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Product Overview
Product Name GW6471
CAS880635-03-0
FormulaC35H36F3N3O4
MW619.67
MDLMFCD07784503
Product details

GW6471 is a PPARα antagonist, which completely inhibits GW409544-induced activation of PPARα with an IC50 = 0.24 μM. GW6471 induces a PPARα conformation that interacts efficiently with co-repressors.GW6471 prevents apoptosis and cell cycle arrest at G0/G1 in renal cell carcinoma. It reduces enhanced fatty acid oxidation and oxidative phosphorylation associated with glycolysis inhibition.

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