Anti-Human PCSK9 Monoclonal Antibody(Evolocumab) | AMG 145

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
1 mg	3-5days	$600.00	Visible after login	- +
5 mg	3-5days	$1600.00	Visible after login	- +
10 mg	3-5days	$2800.00	Visible after login	- +
50 mg	3-5days	$13000.00	Visible after login	- +
100 mg	3-5days	$20000.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

1 mg

3-5days

$600.00

Visible after login

- +

5 mg

3-5days

$1600.00

Visible after login

- +

10 mg

3-5days

$2800.00

Visible after login

- +

50 mg

3-5days

$13000.00

Visible after login

- +

100 mg

3-5days

$20000.00

Visible after login

- +

Product Overview

Product Name	Anti-Human PCSK9 Monoclonal Antibody(Evolocumab); AMG 145
CAS	1256937-27-5
Appearance	Colorless to light yellow (Solution)
Storage condition	Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles.

Product details

Evolocumab (AMG 145) is a human monoclonal antibody that inhibits PCSK9. Evolocumab is used in the study of hypercholesterolemia and atherosclerotic cardiovascular disease. Evolocumab binds to circulating PCSK9 protein and inhibits its binding to LDLR. Evolocumab has antioxidant and cytoprotective activities against H2O2-induced oxidative damage to endothelial cells. Evolocumab may also negatively regulate activation of the TLR-4/NF-κB signaling pathway to prevent inflammation.

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