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Thalidomide-4-OH | Cereblon ligand 2 | E3 ligase Ligand 2)

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Catalog No：CLR1331 CAS No.：5054-59-1 MDLNo：MFCD03699892 Formula：C13H10N2O5 MW：274.23

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Product Overview

Product Name	Thalidomide-4-OH \| Cereblon ligand 2 \| E3 ligase Ligand 2)
CAS	5054-59-1
Formula	C13H10N2O5
MW	274.23
MDL	MFCD03699892
Appearance	White to gray powder
Storage condition	4°C, stored under nitroge

Product details

Thalidomide-4-OH (Cereblon ligand 2) is the Thalidomide-based Cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-OH (Cereblon ligand 2) can be connected to the ligand for protein by a linker to form PROTACs.

Related literature

Effects of putative hydroxylated thalidomide metabolites on blood vessel density in the chorioallantoic membrane (CAM) assay and on tumor and endothelial cell proliferation.

PMID: 12033499 DOI: 10.1248/bpb.25.597

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CLR1331

Thalidomide-4-OH | Cereblon ligand 2 | E3 ligase Ligand 2)

5054-59-1 98+%