Hyperforin

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
1 mg	3-5days	$236.00	Visible after login	- +
2 mg	3-5days	$326.00	Visible after login	- +
5 mg	3-5days	$606.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

1 mg

3-5days

$236.00

Visible after login

- +

2 mg

3-5days

$326.00

Visible after login

- +

5 mg

3-5days

$606.00

Visible after login

- +

Product Overview

Product Name	Hyperforin
CAS	11079-53-1
Formula	C35H52O4
MW	536.785
Appearance	Light yellow to light yellow waxy solid
Storage condition	Fill with nitrogen or dissolve in polar solvents and store in a low temperature environment below -30 ℃ away from light.

Product details

Hyperforin is a transient receptor canonical 6 (TRPC6) channels activator. Hyperforin modulates Ca2+ levels by activating Ca2+-conducting non-selective canonical TRPC6 channels. Hyperforin also shows diverse pharmacological activities including anti-depression, anti-tumor, anti-dementia, anti-diabetes. Hyperforin modulates γδ T cells to secret IL-17α, improves Imiquimod (HY-B0180)-induced psoriasis-like mice model.

Related literature

TRPC6 channel-mediated neurite outgrowth in PC12 cells and hippocampal neurons involves activation of RAS/MEK/ERK, PI3K, and CAMKIV signaling.

PMID: 23875811 DOI: 10.1111/jnc.12376

Hyperforin Potentiates Antidepressant-Like Activity of Lanicemine in Mice.

PMID: 30618608 PMCID: PMC6299069 DOI: 10.3389/fnmol.2018.00456

Biosynthesis of hyperforin in Hypericum perforatum.

PMID: 12361406 DOI: 10.1021/jm0209782

Hyperforin Ameliorates Imiquimod-Induced Psoriasis-Like Murine Skin Inflammation by Modulating IL-17A-Producing γδ T Cells.

PMID: 34025642 PMCID: PMC8131513 DOI: 10.3389/fimmu.2021.635076