Mogroside V ；CAS: 88901-36-4

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Product Overview

Product Name	Mogroside V
CAS	88901-36-4
Formula	C60H102O29
MW	1,287.43
MDL	MFCD00238649
Appearance	White to off-white powder
Storage condition	4°C, protect from light

Product details

Mogroside V, a key active component in Siraitiae Fructus, is a potent non-sugar sweetener with an in vitro AMPK-activating effect. It demonstrates anti-inflammatory properties in murine macrophages and a murine ear edema model, and it may protect against LPS-induced airway inflammation in acute lung injury (ALI) models. This triterpenoid glycoside also possesses antioxidant capabilities, mitigates intracellular reactive oxygen species (ROS) levels, and enhances mitochondrial function. Mogroside V exhibits anti-oxidative, anti-diabetic, and anti-carcinogenic effects, making it a valuable compound for diabetes research. It is particularly relevant for pancreatic cancer models, where it inhibits tumor growth.

Related literature

Mogroside V improves porcine oocyte in vitro maturation and subsequent embryonic development.

PMID: 31518726 DOI: 10.1016/j.theriogenology.2019.09.010

The metabolism of a natural product mogroside V, in healthy and type 2 diabetic rats.

PMID: 29428672 DOI: 10.1016/j.jchromb.2018.02.002

In vitro AMPK activating effect and in vivo pharmacokinetics of mogroside V, a cucurbitane-type triterpenoid from Siraitia grosvenorii fruits[J].

DOI:10.1039/C5RA23275A

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History

(+)-Bicuculline丨D-Bicuculline

485-49-4 98+%

Mogroside V

Chemical safety data sheet(MSDS)