Home > Category > Signaling Pathways > Protein Tyrosine Kinase/RTK > DYRK > Harmine(Banisterine);7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole; 7-Methoxy-1-methyl-9H-beta-carboline;7-methoxy-1-methyl-9H-pyrido[3,4-b]indole

Harmine(Banisterine);7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole; 7-Methoxy-1-methyl-9H-beta-carboline;7-methoxy-1-methyl-9H-pyrido[3,4-b]indole

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Catalog No:HL1454 CAS No.:442-51-3 MDLNo: Formula:C13H12N2O MW:212.25
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Product Overview
Product Name Harmine(Banisterine);7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole; 7-Methoxy-1-methyl-9H-beta-carboline;7-methoxy-1-methyl-9H-pyrido[3,4-b]indole
CAS442-51-3
FormulaC13H12N2O
MW212.25
Storage condition Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Product details

Harmine (telepathine) is a naturally occuring beta-carboline and fluorescent harmala alkaloid found in a number of different plants, most notably the Middle Eastern plant harmal or Syrian rue (Peganum harmala) and the South American vine Banisteriopsis caapi (formerly known as 'yage' or 'ayahuasca'). Harmine is a RIMA because it reversibly inhibits the enzyme monoamine oxidase A (MAO-A), which breaks down monoamines. While it does not inhibit the MAO-B variant, harmine binds to MAO-A specifically. In addition, it is an inhibitor of tyrosine phosphorylation-regulated kinase (DYRK) with anti-inflammatory and anti-cancer properties. With a Ki of 397 nM, harmine exhibits a high affinity for the 5-HT2A serotonin receptor.

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