Sepinol

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Size

Availability

Price(USD)

VIP Price (USD)

Quantity

There is no price information at the moment, you can send an inquiry,and we will reply to you as soon as possible.

Product Overview

Product Name	Sepinol
CAS	72061-63-3
Formula	C16H14O7
MW	318.28
Storage condition	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

Product details

Sepinol is a chromene-type natural product that is structurally related to the flavonoid class of plant compounds. This compound has been shown to inhibit LPS-induced macrophage activation and proinflammatory cytokine production in vitro. Sepinol also inhibits the production of reactive oxygen species by macrophages, which is thought to be due to its ability to inhibit NADPH oxidase activity and the expression of HIF-1α, a transcription factor that regulates many genes involved in inflammation. Sepinol also contains a hydroxy group on its chromene ring, which may explain its chromatographic behavior as well as its resistance against oxidative degradation. The conformation of this molecule suggests that it could be substituted at positions 2 or 3 with a hydroxy group.

Related literature

Structure-activity relationship of the inhibitory effects of flavonoids on nitric oxide production in RAW264.7 cells.

https://doi.org/10.1016/j.bmc.2016.11.055

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History

HL1786

Sepinol

72061-63-3 98+%

Chemical safety data sheet(MSDS)