Azvudine | RO-0622 | FNC | CAS 1011529-10-4

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Product Overview

Product Name	Azvudine (Synonyms: RO-0622; FNC; 4'-C-Azido-2'-deoxy-2'-fluoro-β-D-arabinocytidine)
CAS	1011529-10-4
Formula	C9H11FN6O4
MW	286.22
Appearance	White to off-white powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Azvudine (RO-0622) is a novel nucleoside reverse transcriptase inhibitor with antiviral activity against human immunodeficiency virus (HIV), hepatitis B virus (HBV) and hepatitis C virus (HCV), potently inhibits HIV-1 (EC50 range 0.03 to 6.92 nM) and HIV-2 (EC50s ranging from 0.018 to 0.025 nM).

Related literature

Azvudine, a novel nucleoside reverse transcriptase inhibitor showed good drug combination features and better inhibition on drug-resistant strains than lamivudine in vitro

PMID: 25144636 PMCID: PMC4140803 DOI: 10.1371/journal.pone.0105617

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History

CL1196

Azvudine (Synonyms: RO-0622; FNC; 4'-C-Azido-2'-deoxy-2'-fluoro-β-D-arabinocytidine)

1011529-10-4 99+%