Quizartinib (AC220) | 950769-58-1

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
5 mg	3-5days	$113.00	Visible after login	- +
10 mg	3-5days	$163.00	Visible after login	- +
25 mg	3-5days	$238.00	Visible after login	- +

Product Overview

Product Name	Quizartinib (Synonyms: AC220; AC708)
CAS	950769-58-1
Formula	C29H32N6O4S
MW	560.67
Appearance	White to off-white powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

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Product details

Quizartinib (formerly also know as AC-220; AC-010220, Vanflyta) is a novel, potent, 2nd-generation, and orally bioavailable FLT3 tyrosine kinase inhibitor for Flt3 (ITD/WT) with potential anticancer activity.With IC50s of 1.1 nM and 4.2 nM, respectively, it inhibits FLT3 in MV4-11 and RS4EL11 cells. With respect to KIT, PDGFRα, PDGFRβ, RET, and CSF-1R, it demonstrates a ten-fold greater selectivity. Currently, Daiichi Sankyo is developing quizartinib to treat acute myeloid leukemia. Quizartinib (Vanflyta) was approved in 2023 by FDA for treating AML.
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History

CL2519

Quizartinib (Synonyms: AC220; AC708)

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Quizartinib (Synonyms: AC220; AC708)

Chemical safety data sheet(MSDS)