Cobimetinib | GDC-0973 | XL518 | 934660-93-2

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
5 mg	In-stock	$450.00	Visible after login	- +
10 mg	In-stock	$510.00	Visible after login	- +
50 mg	In-stock	$1200.00	Visible after login	- +

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

5 mg

In-stock

$450.00

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- +

10 mg

In-stock

$510.00

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- +

50 mg

In-stock

$1200.00

Visible after login

- +

Product Overview

Product Name	(S)-(3,4-Difluoro-2-((2-fluoro-4-iodophenyl)amino)phenyl)(3-hydroxy-3-(piperidin-2-yl)azetidin-1-yl)methanone; Cobimetinib (Synonyms: GDC-0973; XL518; RG7420)
CAS	934660-93-2
Formula	C21H21F3IN3O2
MW	531.31
MDL	MFCD22124461
Appearance	Off-white solid powder
Storage condition	Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).

Product details

Cobimetinib (GDC-0973, RG7420) is a potent and highly selective MEK1 inhibitor with IC50 of 4.2 nM, and showing no significant inhibition when tested against a panel of more than 100 of serine-threonine and tyrosine kinases. Cobimetinib induces apoptosis. Phase 3.
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History

CL1287

(S)-(3,4-Difluoro-2-((2-fluoro-4-iodophenyl)amino)phenyl)(3-hydroxy-3-(piperidin-2-yl)azetidin-1-yl)methanone; Cobimetinib (Synonyms: GDC-0973; XL518; RG7420)

934660-93-2 99+%; ee>99%

CL2375

Nilotinib (Synonyms: AMN-107; AMN107)

(S)-(3,4-Difluoro-2-((2-fluoro-4-iodophenyl)amino)phenyl)(3-hydroxy-3-(piperidin-2-yl)azetidin-1-yl)methanone; Cobimetinib (Synonyms: GDC-0973; XL518; RG7420)

Chemical safety data sheet(MSDS)

Certificate Of Authenticity(CPA)